Version 5.4
| Bos taurus Gene: PFDN6 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-629004.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | PFDN6 | ||||||||
| Gene Name | Prefoldin subunit 6 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000010723 | ||||||||
| Encoded Proteins |
Prefoldin subunit 6
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204220:
PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999 [PubMed 10209023]).[supplied by OMIM, Jul 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 23:7405845-7407102 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
Protein folding pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Prefoldin mediated transfer of substrate to CCT/TriC pathway
Protein folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Chaperonin-mediated protein folding pathway
Metabolism of proteins pathway
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding pathway
Protein folding pathway
Prefoldin mediated transfer of substrate to CCT/TriC pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | |||||||||
| RefSeq | NM_001075421 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||