Version 5.4
Bos taurus Gene: IL31RA
Summary
InnateDB Gene IDBG-629108.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL31RA
Gene Name interleukin-31 receptor subunit alpha precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004351
Encoded Proteins
IDBP-680504
interleukin 31 receptor A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164509:
The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:23305806-23355111
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005692 ENSBTAP00000005692
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007259 JAK-STAT cascade
GO:0008284 positive regulation of cell proliferation
GO:0030224 monocyte differentiation
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164509
View Gene Order
ENSMUSG00000050377
View Gene Order
Cross-References
SwissProt
TrEMBL F1MSV1
UniProt Splice Variant
Entrez Gene 522636
UniGene Bt.106477
RefSeq NM_001192563 XM_005221496
HUGO HGNC:18969
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02050337
GenPept
RNA Seq Atlas 522636

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca