Version 5.4
Mus musculus Gene: Il31ra
Summary
InnateDB Gene IDBG-182603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il31ra
Gene Name interleukin 31 receptor A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000050377
Encoded Proteins
IDBP-182605
interleukin 31 receptor A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164509:
The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:112522810-112580662
Strand Reverse strand
Band D2.2
Transcripts
ENSMUST00000051756 ENSMUSP00000058045
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0007259 JAK-STAT cascade
GO:0008284 positive regulation of cell proliferation
GO:0019221 cytokine-mediated signaling pathway
GO:0030224 monocyte differentiation
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164509
View Gene Order
ENSBTAG00000004351
Not yet available
Cross-References
SwissProt Q8K5B1
TrEMBL
UniProt Splice Variant
Entrez Gene 218624
UniGene Mm.380801 Mm.451224
RefSeq NM_139299 XM_006517621 XM_006517622
OMIM
CCDS CCDS36781
HPRD
IMGT
MGI ID MGI:2180511
MGI Symbol Il31ra
EMBL AB083111 AC154767 AC159196 AF486621 AK030512 AY509150 AY509151 BC066164
GenPept AAH66164 AAM27959 AAS82847 AAS82848 BAB88745 BAC26998
RNA Seq Atlas 218624

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca