Bos taurus Gene: TRPC6 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-629235.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | TRPC6 | ||||||||||||||||
Gene Name | Short transient receptor potential channel 6 | ||||||||||||||||
Synonyms | trp6 | ||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000011227 | ||||||||||||||||
Encoded Proteins |
Short transient receptor potential channel 6
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137672:
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 15:7652988-7714074 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
TRP channels pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Signaling by GPCR pathway
Ion channel transport pathway
Elevation of cytosolic Ca2+ levels pathway
Netrin-1 signaling pathway
Hemostasis pathway
Platelet activation, signaling and aggregation pathway
Transmembrane transport of small molecules pathway
Signal Transduction pathway
Axon guidance pathway
Platelet homeostasis pathway
G alpha (q) signalling events pathway
GPCR downstream signaling pathway
Effects of PIP2 hydrolysis pathway
Role of second messengers in netrin-1 signaling pathway
Platelet calcium homeostasis pathway
Stimuli-sensing channels pathway
Developmental Biology pathway
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KEGG | |||||||||||||||||
INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Stimuli-sensing channels pathway
Elevation of cytosolic Ca2+ levels pathway
Platelet homeostasis pathway
Effects of PIP2 hydrolysis pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Role of second messengers in netrin-1 signaling pathway
Netrin-1 signaling pathway
Transmembrane transport of small molecules pathway
Developmental Biology pathway
Platelet calcium homeostasis pathway
Signaling by GPCR pathway
Platelet activation, signaling and aggregation pathway
Axon guidance pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Ion channel transport pathway
TRP channels pathway
Hemostasis pathway
Stimuli-sensing channels pathway
GPCR downstream signaling pathway
Platelet homeostasis pathway
Hemostasis pathway
Signaling by GPCR pathway
Netrin-1 signaling pathway
Platelet calcium homeostasis pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Platelet activation, signaling and aggregation pathway
Role of second messengers in netrin-1 signaling pathway
Effects of PIP2 hydrolysis pathway
Ion channel transport pathway
Axon guidance pathway
Transmembrane transport of small molecules pathway
Developmental Biology pathway
Elevation of cytosolic Ca2+ levels pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
TRP channels pathway
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KEGG | |||||||||||||||||
INOH | |||||||||||||||||
PID NCI |
Nephrin/Neph1 signaling in the kidney podocyte
PAR1-mediated thrombin signaling events
Endothelins
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Cross-References | |||||||||||||||||
SwissProt | Q9MYW0 | ||||||||||||||||
TrEMBL | F1MND4 Q6L6S2 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 407151 | ||||||||||||||||
UniGene | |||||||||||||||||
RefSeq | |||||||||||||||||
HUGO | |||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | AB179746 AJ271069 DAAA02039924 DAAA02039925 | ||||||||||||||||
GenPept | BAD19016 CAC01677 | ||||||||||||||||
RNA Seq Atlas | 407151 | ||||||||||||||||