InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ASB4

Summary

InnateDB Gene

IDBG-629313.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ASB4

Gene Name

ankyrin repeat and SOCS box protein 4

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000018185

Encoded Proteins

IDBP-680720

ankyrin repeat and SOCS box containing 4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000005981:
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:12597838-12699701

Strand

Forward strand

Band

Transcripts

ENSBTAT00000024202

ENSBTAP00000024202

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0031625	ubiquitin protein ligase binding

Biological Process

GO:0016567	protein ubiquitination
GO:0035556	intracellular signal transduction
GO:0051865	protein autoubiquitination
GO:2001214	positive regulation of vasculogenesis