Version 5.4
Bos taurus Gene: C1GALT1
Summary
InnateDB Gene IDBG-629436.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C1GALT1
Gene Name Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004995
Encoded Proteins
IDBP-680843
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106392:
The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.[provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:15183826-15227662
Strand Forward strand
Band
Transcripts
ENSBTAT00000006572 ENSBTAP00000006571
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008378 galactosyltransferase activity
GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
GO:0046872 metal ion binding
Biological Process
GO:0001525 angiogenesis
GO:0001822 kidney development
GO:0006486 protein glycosylation
GO:0007275 multicellular organismal development
GO:0016266 O-glycan processing
GO:0030154 cell differentiation
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000106392
View Gene Order
ENSMUSG00000042460
View Gene Order
Pathways
NETPATH
REACTOME
REACT_216510
O-linked glycosylation pathway
REACT_213782
Metabolism of proteins pathway
REACT_214405
Post-translational protein modification pathway
REACT_208023
O-linked glycosylation of mucins pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115606
O-linked glycosylation of mucins pathway
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
REACT_198517
O-linked glycosylation of mucins pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_204003
O-linked glycosylation pathway
KEGG
hsa00512
Mucin type O-Glycan biosynthesis pathway
mmu00512
Mucin type O-Glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q0VC84
TrEMBL
UniProt Splice Variant
Entrez Gene 539417
UniGene Bt.22740
RefSeq NM_001076160 XM_005205157 XM_005205158 XM_005205159
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120299
GenPept AAI20300
RNA Seq Atlas 539417

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca