Bos taurus Gene: ADAM2
Summary
InnateDB Gene IDBG-629478.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM2
Gene Name disintegrin and metalloproteinase domain-containing protein 2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009408
Encoded Proteins
disintegrin and metalloproteinase domain-containing protein 2 precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104755:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. [provided by RefSeq, Jul 2008]
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 27:34249449-34353369
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012384 ENSBTAP00000012384
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0007155 cell adhesion
GO:0008542 visual learning
GO:0030534 adult behavior
Cellular Component
GO:0009986 cell surface
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Interaction With The Zona Pellucida pathway
Fertilization pathway
Reproduction pathway
Fertilization pathway
Reproduction pathway
Interaction With The Zona Pellucida pathway
KEGG
INOH
PID NCI
Alpha9 beta1 integrin signaling events
Cross-References
SwissProt
TrEMBL G1K1H0
UniProt Splice Variant
Entrez Gene 281599
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02060876 DAAA02060877 DAAA02060878 DAAA02060879 DAAA02060880 DAAA02060881 DAAA02060882 DAAA02060883
GenPept
RNA Seq Atlas 281599