Version 5.4
Bos taurus Gene: PACSIN1
Summary
InnateDB Gene IDBG-629496.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PACSIN1
Gene Name Protein kinase C and casein kinase substrate in neurons protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016124
Encoded Proteins
IDBP-680905
Protein kinase C and casein kinase substrate in neurons protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 22488361
[Homo sapiens] PACSIN1 regulates the TLR7/9-mediated type I interferon response in plasmacytoid dendritic cells.
PMID 22488361
[Mus musculus] Pacsin1 regulates the Tlr7/9-mediated type I interferon response in plasmacytoid dendritic cells.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124507:
Gene Information
Type Protein coding
Genomic Location Chromosome 23:8469769-8534469
Strand Forward strand
Band
Transcripts
ENSBTAT00000021459 ENSBTAP00000021459
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0008092 cytoskeletal protein binding
GO:0008289 lipid binding
Biological Process
GO:0006897 endocytosis
GO:0007015 actin filament organization
GO:0045806 negative regulation of endocytosis
GO:0048488 synaptic vesicle endocytosis
GO:0048666 neuron development
GO:0048812 neuron projection morphogenesis
GO:0072657 protein localization to membrane
GO:0097320 membrane tubulation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030054 cell junction
GO:0030137 COPI-coated vesicle
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0032587 ruffle membrane
GO:0042995 cell projection
GO:0043005 neuron projection
GO:0043679 axon terminus
GO:0045202 synapse
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000124507
View Gene Order
ENSMUSG00000040276
View Gene Order
Cross-References
SwissProt A7MBI0
TrEMBL
UniProt Splice Variant
Entrez Gene 520488
UniGene Bt.35936
RefSeq NM_001101101 XM_005223249
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151572 BC153241
GenPept AAI51573 AAI53242
RNA Seq Atlas 520488

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca