Bos taurus Gene: SLC25A5
Summary
InnateDB Gene IDBG-629613.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A5
Gene Name ADP/ATP translocase 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000046037
Encoded Proteins
ADP/ATP translocase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000005022:
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Sep 2009]
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome X:3696978-3701262
Strand Forward strand
Band
Transcripts
ENSBTAT00000064551 ENSBTAP00000056626
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 81 interaction(s) predicted by orthology.
Predicted by orthology
Total 81 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006810 transport
GO:0007059 chromosome segregation
GO:0008284 positive regulation of cell proliferation
GO:0055085 transmembrane transport
GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042645 mitochondrial nucleoid
GO:0070062 extracellular vesicular exosome
GO:0071817 MMXD complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization pathway
Interactions of Vpr with host cellular proteins pathway
HIV Infection pathway
Metabolism pathway
Host Interactions of HIV factors pathway
Disease pathway
Integration of energy metabolism pathway
Metabolism pathway
Regulation of insulin secretion pathway
KEGG
Calcium signaling pathway pathway
Parkinson's disease pathway
Huntington's disease pathway
Calcium signaling pathway pathway
Parkinson's disease pathway
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_174659
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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