Version 5.4
Bos taurus Gene: BT.53537
Summary
InnateDB Gene IDBG-629758.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.53537
Gene Name dynein assembly factor 1, axonemal
Synonyms LLRC50; LRRC50
Species Bos taurus
Ensembl Gene ENSBTAG00000018771
Encoded Proteins
IDBP-681186
leucine-rich repeat-containing protein 50
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154099:
The protein encoded by this gene is cilium-specific and is required for the stability of the ciliary architecture. It is involved in the regulation of microtubule-based cilia and actin-based brush border microvilli. Mutations in this gene are associated with primary ciliary dyskinesia-13.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:10451369-10472288
Strand Forward strand
Band
Transcripts
ENSBTAT00000024994 ENSBTAP00000024994
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0045502 dynein binding
Biological Process
GO:0001947 heart looping
GO:0003341 cilium movement
GO:0003356 regulation of cilium beat frequency
GO:0030324 lung development
GO:0035469 determination of pancreatic left/right asymmetry
GO:0036158 outer dynein arm assembly
GO:0036159 inner dynein arm assembly
GO:0044458 motile cilium assembly
GO:0060271 cilium morphogenesis
GO:0060972 left/right pattern formation
GO:0070286 axonemal dynein complex assembly
GO:0071907 determination of digestive tract left/right asymmetry
GO:0071910 determination of liver left/right asymmetry
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005930 axoneme
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000154099
View Gene Order
ENSMUSG00000031831
View Gene Order
Cross-References
SwissProt
TrEMBL F1MTA8
UniProt Splice Variant
Entrez Gene 523187
UniGene Bt.53537
RefSeq NM_001035345
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046171 DAAA02046172
GenPept
RNA Seq Atlas 523187

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca