InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RXRG

Summary

InnateDB Gene

IDBG-629761.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RXRG

Gene Name

Retinoic acid receptor RXR-gamma

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000016801

Encoded Proteins

IDBP-681175

Retinoic acid receptor RXR-gamma

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143171:
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:3576688-3636911

Strand

Forward strand

Band

Transcripts

ENSBTAT00000022350

ENSBTAP00000022350

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0004886	9-cis retinoic acid receptor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0043401	steroid hormone mediated signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048384	retinoic acid receptor signaling pathway