Version 5.4
| Bos taurus Gene: SLC7A11 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-629829.3 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | SLC7A11 | ||||||||||||
| Gene Name | Uncharacterized protein | ||||||||||||
| Synonyms | |||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Gene | ENSBTAG00000034075 | ||||||||||||
| Encoded Proteins |
Uncharacterized protein
Uncharacterized protein
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| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151012:
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 17:19729366-19808282 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | |||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Basigin interactions pathway
Cell surface interactions at the vascular wall pathway
Amino acid transport across the plasma membrane pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
Hemostasis pathway
Hemostasis pathway
SLC-mediated transmembrane transport pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Cell surface interactions at the vascular wall pathway
Basigin interactions pathway
Transmembrane transport of small molecules pathway
Amino acid transport across the plasma membrane pathway
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| KEGG | |||||||||||||
| INOH | |||||||||||||
| PID NCI | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | B6D7N9 F1N5E3 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 524078 | ||||||||||||
| UniGene | Bt.104135 | ||||||||||||
| RefSeq | XM_002694373 XM_003583290 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | DAAA02044458 DAAA02044459 DAAA02044460 EU861216 | ||||||||||||
| GenPept | ACI00423 | ||||||||||||
| RNA Seq Atlas | 524078 | ||||||||||||