Version 5.4
Bos taurus Gene: CDH23
Summary
InnateDB Gene IDBG-629834.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDH23
Gene Name cadherin-23 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021497
Encoded Proteins
IDBP-681329
cadherin-related 23
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107736:
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 28:27729164-28123449
Strand Forward strand
Band
Transcripts
ENSBTAT00000028652 ENSBTAP00000028652
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
GO:0007605 sensory perception of sound
GO:0007626 locomotory behavior
GO:0042472 inner ear morphogenesis
GO:0042491 auditory receptor cell differentiation
GO:0048563 post-embryonic organ morphogenesis
GO:0048839 inner ear development
GO:0050953 sensory perception of light stimulus
GO:0060088 auditory receptor cell stereocilium organization
Cellular Component
GO:0001917 photoreceptor inner segment
GO:0005813 centrosome
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032420 stereocilium
GO:0032426 stereocilium bundle tip
GO:0045202 synapse
GO:0060091 kinocilium
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000107736
View Gene Order
ENSMUSG00000012819
View Gene Order
Cross-References
SwissProt
TrEMBL F1MXP9
UniProt Splice Variant
Entrez Gene 784716
UniGene Bt.75498
RefSeq NM_001191206
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02061863 DAAA02061864 DAAA02061865 DAAA02061866 DAAA02061867 DAAA02061868
GenPept
RNA Seq Atlas 784716

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca