Version 5.4
| Bos taurus Gene: EXOSC8 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-629856.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | EXOSC8 | ||||||||
| Gene Name | Exosome complex component RRP43 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000011855 | ||||||||
| Encoded Proteins |
Exosome complex component RRP43
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000120699:
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2009] This gene encodes a 3\'-5\' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2009] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 12:24708380-24717631 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
KSRP destabilizes mRNA pathway
PERK regulates gene expression pathway
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
ATF4 activates genes pathway
Gene Expression pathway
Metabolism of proteins pathway
mRNA decay by 3' to 5' exoribonuclease pathway
Unfolded Protein Response (UPR) pathway
Deadenylation-dependent mRNA decay pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Butyrate Response Factor 1 (BRF1) destabilizes mRNA pathway
Tristetraprolin (TTP) destabilizes mRNA pathway
KSRP destabilizes mRNA pathway
mRNA decay by 3' to 5' exoribonuclease pathway
ATF4 activates genes pathway
PERK regulates gene expression pathway
Unfolded Protein Response (UPR) pathway
Deadenylation-dependent mRNA decay pathway
Metabolism of proteins pathway
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
Gene Expression pathway
mRNA decay by 3' to 5' exoribonuclease pathway
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
KSRP destabilizes mRNA pathway
Gene Expression pathway
Deadenylation-dependent mRNA decay pathway
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| KEGG |
RNA degradation pathway
RNA degradation pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q2KHU3 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 532080 | ||||||||
| UniGene | |||||||||
| RefSeq | NM_001079606 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC112881 | ||||||||
| GenPept | AAI12882 | ||||||||
| RNA Seq Atlas | 532080 | ||||||||