Bos taurus Gene: GRIA3 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-629894.3 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | GRIA3 | ||||||||||||||||
Gene Name | glutamate receptor 3 precursor | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Bos taurus | ||||||||||||||||
Ensembl Gene | ENSBTAG00000011833 | ||||||||||||||||
Encoded Proteins |
glutamate receptor, ionotrophic, AMPA 3
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125675:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008] Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome X:7180735-7482667 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | |||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Unblocking of NMDA receptor, glutamate binding and activation pathway
Trafficking of GluR2-containing AMPA receptors pathway
Trafficking of AMPA receptors pathway
Activation of AMPA receptors pathway
Neuronal System pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
Activation of AMPA receptors pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity pathway
Neuronal System pathway
Unblocking of NMDA receptor, glutamate binding and activation pathway
Trafficking of GluR2-containing AMPA receptors pathway
Trafficking of AMPA receptors pathway
Transmission across Chemical Synapses pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
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KEGG |
Neuroactive ligand-receptor interaction pathway
Long-term depression pathway
Neuroactive ligand-receptor interaction pathway
Long-term depression pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | E1BGZ0 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 534626 | ||||||||||||||||
UniGene | Bt.18701 | ||||||||||||||||
RefSeq | NM_001206059 XM_005227468 XM_005227469 | ||||||||||||||||
HUGO | HGNC:4573 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | |||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
EMBL | DAAA02067291 DAAA02067292 DAAA02067293 DAAA02067294 | ||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | 534626 | ||||||||||||||||