Version 5.4
Bos taurus Gene: DIXDC1
Summary
InnateDB Gene IDBG-630338.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DIXDC1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008665
Encoded Proteins
IDBP-681843
DIX domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150764:
The protein encoded by this gene is a positive regulator of the Wnt signaling pathway and interacts with AXIN1, DVL2, and MAP3K1. The encoded protein is found associated with gamma tubulin at the centrosome. Three transcript variants, two protein-coding and the other non-protein coding, have been found for this gene. The longer isoform also associates with actin stress fibers while the shorter isoform does not. [provided by RefSeq, Feb 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:22614860-22659906
Strand Forward strand
Band
Transcripts
ENSBTAT00000040095 ENSBTAP00000039875
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0043015 gamma-tubulin binding
Biological Process
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0007275 multicellular organismal development
GO:0021795 cerebral cortex cell migration
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021846 cell proliferation in forebrain
GO:0021869 forebrain ventricular zone progenitor cell division
GO:0030177 positive regulation of Wnt signaling pathway
GO:0032956 regulation of actin cytoskeleton organization
GO:0045665 negative regulation of neuron differentiation
GO:0070507 regulation of microtubule cytoskeleton organization
GO:0090263 positive regulation of canonical Wnt signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000150764
View Gene Order
ENSMUSG00000032064
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_8
Wnt pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MD63
UniProt Splice Variant
Entrez Gene 541211
UniGene
RefSeq XM_002693011 XM_005194575 XM_005215883 XM_615064
HUGO HGNC:23695
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02040284 DAAA02040285
GenPept
RNA Seq Atlas 541211

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca