Version 5.4
Bos taurus Gene: TRPM1
Summary
InnateDB Gene IDBG-630449.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRPM1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001639
Encoded Proteins
IDBP-681982
transient receptor potential cation channel, subfamily M, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134160:
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:27993518-28055083
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010233 ENSBTAP00000010233
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0007165 signal transduction
GO:0007216 G-protein coupled glutamate receptor signaling pathway
GO:0007601 visual perception
GO:0046548 retinal rod cell development
GO:0055085 transmembrane transport
GO:0060402 calcium ion transport into cytosol
GO:0071482 cellular response to light stimulus
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0035841 new growing cell tip
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000134160
View Gene Order
ENSMUSG00000030523
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
REACT_196640
Stimuli-sensing channels pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_227861
TRP channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MPU3
UniProt Splice Variant
Entrez Gene 527638
UniGene Bt.88420
RefSeq XM_002696605 XM_606035
HUGO HGNC:7146
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02052355 DAAA02052356
GenPept
RNA Seq Atlas 527638

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca