Version 5.4
Mus musculus Gene: Trpm1
Summary
InnateDB Gene IDBG-190849.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trpm1
Gene Name transient receptor potential cation channel, subfamily M, member 1
Synonyms 4732499L03Rik; AI606771; Ltrpc1; melastatin; Mlsn1
Species Mus musculus
Ensembl Gene ENSMUSG00000030523
Encoded Proteins
IDBP-190855
transient receptor potential cation channel, subfamily M, member 1
IDBP-190857
transient receptor potential cation channel, subfamily M, member 1
IDBP-266474
transient receptor potential cation channel, subfamily M, member 1
IDBP-266476
transient receptor potential cation channel, subfamily M, member 1
IDBP-266480
transient receptor potential cation channel, subfamily M, member 1
IDBP-266486
transient receptor potential cation channel, subfamily M, member 1
IDBP-722670
IDBP-532576
transient receptor potential cation channel, subfamily M, member 1
IDBP-532588
transient receptor potential cation channel, subfamily M, member 1
IDBP-722709
IDBP-722721
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134160:
This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:64153835-64269775
Strand Forward strand
Band C
Transcripts
ENSMUST00000032737 ENSMUSP00000032737
ENSMUST00000085222 ENSMUSP00000082318
ENSMUST00000107527 ENSMUSP00000103151
ENSMUST00000107525 ENSMUSP00000103149
ENSMUST00000107519 ENSMUSP00000103143
ENSMUST00000107516
ENSMUST00000107515 ENSMUSP00000103139
ENSMUST00000153421 ENSMUSP00000135595
ENSMUST00000141574
ENSMUST00000146313
ENSMUST00000137650 ENSMUSP00000118181
ENSMUST00000144996 ENSMUSP00000116626
ENSMUST00000140277
ENSMUST00000138074
ENSMUST00000138609
ENSMUST00000124597
ENSMUST00000155787
ENSMUST00000176392
ENSMUST00000176623 ENSMUSP00000134805
ENSMUST00000176548
ENSMUST00000177102 ENSMUSP00000134947
ENSMUST00000177295
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
Biological Process
GO:0006811 ion transport
GO:0006812 cation transport
GO:0007165 signal transduction
GO:0007216 G-protein coupled glutamate receptor signaling pathway
GO:0007601 visual perception
GO:0034220 ion transmembrane transport
GO:0046548 retinal rod cell development
GO:0055085 transmembrane transport
GO:0060402 calcium ion transport into cytosol
GO:0070588 calcium ion transmembrane transport
GO:0071482 cellular response to light stimulus
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0035841 new growing cell tip
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134160
View Gene Order
ENSBTAG00000001639
Not yet available
Pathways
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_227861
TRP channels pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.38875 Mm.404453
RefSeq NM_001039104 NM_018752 XM_006540690
OMIM
CCDS CCDS21332 CCDS39975
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca