Version 5.4
Bos taurus Gene: NPR3
Summary
InnateDB Gene IDBG-630625.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPR3
Gene Name atrial natriuretic peptide receptor 3 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007665
Encoded Proteins
IDBP-682105
atrial natriuretic peptide receptor 3 precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113389:
This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:40967082-41041629
Strand Reverse strand
Band
Transcripts
ENSBTAT00000036705 ENSBTAP00000036561
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016941 natriuretic peptide receptor activity
GO:0042562 hormone binding
Biological Process
GO:0001501 skeletal system development
GO:0002158 osteoclast proliferation
GO:0008217 regulation of blood pressure
GO:0033688 regulation of osteoblast proliferation
GO:0035810 positive regulation of urine volume
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000113389
View Gene Order
ENSMUSG00000022206
View Gene Order
Cross-References
SwissProt
TrEMBL B0JYL2
UniProt Splice Variant
Entrez Gene 281358
UniGene Bt.376
RefSeq NM_174127
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151352 DAAA02050683 DAAA02050684
GenPept AAI51353
RNA Seq Atlas 281358

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca