Version 5.4
Bos taurus Gene: ZW10
Summary
InnateDB Gene IDBG-630655.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZW10
Gene Name centromere/kinetochore protein zw10 homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020066
Encoded Proteins
IDBP-682127
centromere/kinetochore protein zw10 homolog
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086827:
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:24616731-24652072
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026733 ENSBTAP00000026733
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0000132 establishment of mitotic spindle orientation
GO:0006461 protein complex assembly
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0007067 mitotic nuclear division
GO:0007080 mitotic metaphase plate congression
GO:0007093 mitotic cell cycle checkpoint
GO:0007096 regulation of exit from mitosis
GO:0034501 protein localization to kinetochore
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005828 kinetochore microtubule
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000086827
View Gene Order
ENSMUSG00000032264
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_202512
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.15793 Bt.68870
RefSeq NM_001075489
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca