Version 5.4
| Bos taurus Gene: CPOX | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-631009.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CPOX | ||||||||
| Gene Name | coproporphyrinogen-III oxidase, mitochondrial | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000004124 | ||||||||
| Encoded Proteins |
coproporphyrinogen oxidase
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000080819:
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 1:42518056-42531538 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Heme biosynthesis pathway
Metabolism of porphyrins pathway
Metabolism pathway
Metabolism pathway
Heme biosynthesis pathway
Metabolism of porphyrins pathway
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| KEGG |
Porphyrin and chlorophyll metabolism pathway
Porphyrin and chlorophyll metabolism pathway
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| INOH |
Porphyrin metabolism pathway
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| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1BKY9 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 540283 | ||||||||
| UniGene | Bt.26709 | ||||||||
| RefSeq | NM_001192393 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02000998 DAAA02000999 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 540283 | ||||||||