Bos taurus Gene: PCLO
Summary
InnateDB Gene IDBG-631067.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCLO
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017350
Encoded Proteins
piccolo (presynaptic cytomatrix protein)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186472:
The protein encoded by this gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:37629861-38018531
Strand Forward strand
Band
Transcripts
ENSBTAT00000033801 ENSBTAP00000033710
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005522 profilin binding
GO:0046872 metal ion binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0017157 regulation of exocytosis
GO:0019933 cAMP-mediated signaling
GO:0030073 insulin secretion
Cellular Component
GO:0045202 synapse
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.103794 Bt.112125 Bt.112155
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas