InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: COL8A1

Summary

InnateDB Gene

IDBG-631089.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COL8A1

Gene Name

collagen alpha-1(VIII) chain precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013662

Encoded Proteins

IDBP-682583

collagen alpha-1(VIII) chain

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144810:
This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:43541936-43717619

Strand

Forward strand

Band

Transcripts

ENSBTAT00000018159

ENSBTAP00000018159

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0010811	positive regulation of cell-substrate adhesion
GO:0048593	camera-type eye morphogenesis
GO:0050673	epithelial cell proliferation

Cellular Component

GO:0005576	extracellular region
GO:0005581	collagen trimer
GO:0031012	extracellular matrix
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome