InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SGCG

Summary

InnateDB Gene

IDBG-631112.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SGCG

Gene Name

Gamma-sarcoglycan

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000001865

Encoded Proteins

IDBP-682612

Gamma-sarcoglycan

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102683:
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:34924193-34954970

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000002431

ENSBTAP00000002431

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0016011	dystroglycan complex
GO:0016012	sarcoglycan complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042383	sarcolemma