Bos taurus Gene: FBXL7 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-631189.3 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | FBXL7 | ||||||||
Gene Name | Uncharacterized protein | ||||||||
Synonyms | |||||||||
Species | Bos taurus | ||||||||
Ensembl Gene | ENSBTAG00000003219 | ||||||||
Encoded Proteins |
F-box and leucine-rich repeat protein 7
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183580:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. [provided by RefSeq, Jul 2008] This gene encodes a member of the F-box protein family which is characterized by a 42-48 amino acid motif, the F-box, which binds to the S-phase kinase-associated protein 1 (Skp1) protein. The F-box proteins constitute one of the four subunits of E3 ubiquitin protein ligases called SCFs (SKP1-Cul1-F-box), which play a role in phosphorylation-dependent ubiquitination of proteins. The F-box proteins are divided into 3 subfamilies based on the other domain in the protein: F-box proteins that also have a WD-40 domain (Fbws subfamily), F-box proteins that also have leucine-rich repeats (Fbls subfamily) and F-box proteins that contain other motifs or lack known protein-interaction domains (Fbxs subfamily). The protein encoded by this gene belongs to the Fbls subfamily. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 20:57300938-57311455 | ||||||||
Strand | Reverse strand | ||||||||
Band | |||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | F1N019 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 518806 | ||||||||
UniGene | |||||||||
RefSeq | XM_002696446 XM_005192873 XM_005221650 XM_597007 | ||||||||
HUGO | HGNC:13604 | ||||||||
OMIM | |||||||||
CCDS | |||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | DAAA02051082 | ||||||||
GenPept | |||||||||
RNA Seq Atlas | 518806 | ||||||||