InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MYLK3

Summary

InnateDB Gene

IDBG-631225.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYLK3

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000014818

Encoded Proteins

IDBP-682738

myosin light chain kinase 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140795:
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:15089441-15131888

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000019734

ENSBTAP00000019734

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004683	calmodulin-dependent protein kinase activity
GO:0004687	myosin light chain kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0002528	regulation of vascular permeability involved in acute inflammatory response
GO:0006468	protein phosphorylation
GO:0016310	phosphorylation
GO:0045214	sarcomere organization
GO:0071347	cellular response to interleukin-1