Version 5.4
Bos taurus Gene: SMYD3
Summary
InnateDB Gene IDBG-631259.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMYD3
Gene Name SET and MYND domain-containing protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000033180
Encoded Proteins
IDBP-682784
SET and MYND domain-containing protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185420:
This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:31589396-32333109
Strand Forward strand
Band
Transcripts
ENSBTAT00000047138 ENSBTAP00000044365
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0000993 RNA polymerase II core binding
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0005515 protein binding
GO:0018024 histone-lysine N-methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006334 nucleosome assembly
GO:0006469 negative regulation of protein kinase activity
GO:0014904 myotube cell development
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0045184 establishment of protein localization
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0071549 cellular response to dexamethasone stimulus
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000185420
View Gene Order
ENSMUSG00000055067
View Gene Order
Cross-References
SwissProt
TrEMBL Q0P5C5
UniProt Splice Variant
Entrez Gene 616050
UniGene Bt.32813
RefSeq NM_001076406
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120241 DAAA02042692 DAAA02042693 DAAA02042694 DAAA02042695 DAAA02042696 DAAA02042697 DAAA02042698 DAAA02042699 DAAA02042700 DAAA02042701 DAAA02042702 DAAA02042703 DAAA02042704 DAAA02042705 DAAA02042706
GenPept AAI20242
RNA Seq Atlas 616050

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca