Version 5.4
| Bos taurus Gene: CD3G | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-631280.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CD3G | ||||||||
| Gene Name | T-cell surface glycoprotein CD3 gamma chain | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000006453 | ||||||||
| Encoded Proteins |
T-cell surface glycoprotein CD3 gamma chain
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160654:
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 15:29462576-29469747 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
PD-1 signaling pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Phosphorylation of CD3 and TCR zeta chains pathway
Costimulation by the CD28 family pathway
Downstream TCR signaling pathway
Immune System pathway
Role of phospholipids in phagocytosis pathway
Regulation of actin dynamics for phagocytic cup formation pathway
FCGR activation pathway
Adaptive Immune System pathway
Innate Immune System pathway
Generation of second messenger molecules pathway
Translocation of ZAP-70 to Immunological synapse pathway
TCR signaling pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
TCR pathway
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| REACTOME |
Regulation of actin dynamics for phagocytic cup formation pathway
Role of phospholipids in phagocytosis pathway
FCGR activation pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Downstream TCR signaling pathway
Generation of second messenger molecules pathway
Translocation of ZAP-70 to Immunological synapse pathway
Phosphorylation of CD3 and TCR zeta chains pathway
PD-1 signaling pathway
Costimulation by the CD28 family pathway
TCR signaling pathway
Innate Immune System pathway
Adaptive Immune System pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
PD-1 signaling pathway
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Role of phospholipids in phagocytosis pathway
Phosphorylation of CD3 and TCR zeta chains pathway
Downstream TCR signaling pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Immune System pathway
FCGR activation pathway
Translocation of ZAP-70 to Immunological synapse pathway
Costimulation by the CD28 family pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Adaptive Immune System pathway
Generation of second messenger molecules pathway
TCR signaling pathway
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| KEGG |
Hematopoietic cell lineage pathway
T cell receptor signaling pathway pathway
Chagas disease (American trypanosomiasis) pathway
Hematopoietic cell lineage pathway
T cell receptor signaling pathway pathway
Chagas disease (American trypanosomiasis) pathway
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| INOH |
CD4 T cell receptor signaling pathway
CD4 T cell receptor signaling pathway
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| PID NCI |
TCR signaling in naïve CD8+ T cells
CXCR4-mediated signaling events
TCR signaling in naïve CD4+ T cells
Downstream signaling in naïve CD8+ T cells
IL12-mediated signaling events
IL12 signaling mediated by STAT4
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Bt.13934 | ||||||||
| RefSeq | NM_001040472 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||