Version 5.4
Bos taurus Gene: NAPEPLD
Summary
InnateDB Gene IDBG-631475.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAPEPLD
Gene Name N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D
Synonyms NAPE-PLD
Species Bos taurus
Ensembl Gene ENSBTAG00000014171
Encoded Proteins
IDBP-683013
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161048:
NAPEPLD is a phospholipase D type enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE) in the second step of the biosynthesis of N-acylethanolamine (Okamoto et al., 2004 [PubMed 14634025]).[supplied by OMIM, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:44665683-44720623
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018833 ENSBTAP00000018833
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity
Biological Process
GO:0006629 lipid metabolic process
GO:0009395 phospholipid catabolic process
GO:0016042 lipid catabolic process
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000161048
View Gene Order
ENSMUSG00000044968
View Gene Order
Pathways
NETPATH
REACTOME
REACT_211834
The canonical retinoid cycle in rods (twilight vision) pathway
REACT_223698
Visual phototransduction pathway
REACT_214353
Signal Transduction pathway
REACT_216038
Diseases associated with visual transduction pathway
REACT_218434
Retinoid cycle disease events pathway
REACT_205105
Biosynthesis of A2E, implicated in retinal degradation pathway
REACT_207087
Disease pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160156
The canonical retinoid cycle in rods (twilight vision) pathway
REACT_160194
Biosynthesis of A2E, implicated in retinal degradation pathway
REACT_160130
Retinoid cycle disease events pathway
REACT_111102
Signal Transduction pathway
REACT_160102
Diseases associated with visual transduction pathway
REACT_160125
Visual phototransduction pathway
REACT_116125
Disease pathway
REACT_189085
Disease pathway
REACT_188277
The canonical retinoid cycle in rods (twilight vision) pathway
REACT_188260
Visual phototransduction pathway
REACT_196615
Retinoid cycle disease events pathway
REACT_188257
Signal Transduction pathway
REACT_188255
Diseases associated with visual transduction pathway
REACT_196613
Biosynthesis of A2E, implicated in retinal degradation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.63822
RefSeq NM_001015680 XM_005205368 XM_005205369
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca