Version 5.4
Bos taurus Gene: BT.77209
Summary
InnateDB Gene IDBG-631619.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.77209
Gene Name eukaryotic translation initiation factor 4B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006883
Encoded Proteins
IDBP-683168
eukaryotic translation initiation factor 4B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000063046:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:27091609-27115819
Strand Reverse strand
Band
Transcripts
ENSBTAT00000009044 ENSBTAP00000009044
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.
Predicted by orthology
Total 43 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
Biological Process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000063046
View Gene Order
ENSMUSG00000058655
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_79
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_6772
S6K1 signalling pathway
REACT_6754
S6K1-mediated signalling pathway
REACT_6838
mTOR signalling pathway
REACT_976
PI3K Cascade pathway
REACT_498
Signaling by Insulin receptor pathway
REACT_150203
IRS-related events triggered by IGF1R pathway
REACT_150359
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
REACT_20514
Deadenylation of mRNA pathway
REACT_2085
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
REACT_1979
Translation initiation complex formation pathway
REACT_1258
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
REACT_931
Ribosomal scanning and start codon recognition pathway
REACT_2159
Eukaryotic Translation Initiation pathway
REACT_456
PKB-mediated events pathway
REACT_20639
Deadenylation-dependent mRNA decay pathway
REACT_6964
mTORC1-mediated signalling pathway
REACT_1014
Translation pathway
REACT_111102
Signal Transduction pathway
REACT_332
IRS-mediated signalling pathway
REACT_17015
Metabolism of proteins pathway
REACT_1195
Insulin receptor signalling cascade pathway
REACT_2099
Cap-dependent Translation Initiation pathway
REACT_762
IRS-related events pathway
REACT_150210
IGF1R signaling cascade pathway
REACT_71
Gene Expression pathway
REACT_240250
Signaling by Insulin receptor pathway
REACT_255163
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
REACT_229737
S6K1 signalling pathway
REACT_244119
Deadenylation of mRNA pathway
REACT_254308
Translation pathway
REACT_256488
Translation initiation complex formation pathway
REACT_247926
Metabolism of proteins pathway
REACT_229570
Cap-dependent Translation Initiation pathway
REACT_262064
Eukaryotic Translation Initiation pathway
REACT_259732
Insulin receptor signalling cascade pathway
REACT_260675
S6K1-mediated signalling pathway
REACT_188215
IRS-related events triggered by IGF1R pathway
REACT_188218
IGF1R signaling cascade pathway
REACT_188219
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
REACT_240139
PI3K Cascade pathway
REACT_233572
Gene Expression pathway
REACT_243154
IRS-related events pathway
REACT_242206
IRS-mediated signalling pathway
REACT_231630
mTORC1-mediated signalling pathway
REACT_259469
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_188257
Signal Transduction pathway
REACT_236458
Ribosomal scanning and start codon recognition pathway
REACT_255725
mTOR signalling pathway
REACT_256714
PKB-mediated events pathway
REACT_262078
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
REACT_235784
Deadenylation-dependent mRNA decay pathway
KEGG
hsa04150
mTOR signaling pathway pathway
hsa03013
RNA transport pathway
mmu04150
mTOR signaling pathway pathway
mmu03013
RNA transport pathway
INOH
PID NCI
mtor_4pathway
mTOR signaling pathway
Cross-References
SwissProt
TrEMBL F1MYS7
UniProt Splice Variant
Entrez Gene 505850
UniGene Bt.77209
RefSeq NM_001035028 XM_005206207
HUGO HGNC:3285
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02012872 DAAA02012873
GenPept
RNA Seq Atlas 505850

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca