Homo sapiens Gene: EIF4B | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-35510.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | EIF4B | ||||||||||||||||||||||
Gene Name | eukaryotic translation initiation factor 4B | ||||||||||||||||||||||
Synonyms | EIF-4B; PRO1843 | ||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000063046 | ||||||||||||||||||||||
Encoded Proteins |
eukaryotic translation initiation factor 4B
eukaryotic translation initiation factor 4B
eukaryotic translation initiation factor 4B
eukaryotic translation initiation factor 4B
eukaryotic translation initiation factor 4B
eukaryotic translation initiation factor 4B
eukaryotic translation initiation factor 4B
eukaryotic translation initiation factor 4B
eukaryotic translation initiation factor 4B
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary | Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs. | ||||||||||||||||||||||
Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 12:53006158-53042209 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | q13.13 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 70 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
L13a-mediated translational silencing of Ceruloplasmin expression pathway
S6K1 signalling pathway
S6K1-mediated signalling pathway
mTOR signalling pathway
PI3K Cascade pathway
Signaling by Insulin receptor pathway
IRS-related events triggered by IGF1R pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
Deadenylation of mRNA pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Translation initiation complex formation pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Ribosomal scanning and start codon recognition pathway
Eukaryotic Translation Initiation pathway
PKB-mediated events pathway
Deadenylation-dependent mRNA decay pathway
mTORC1-mediated signalling pathway
Translation pathway
Signal Transduction pathway
IRS-mediated signalling pathway
Metabolism of proteins pathway
Insulin receptor signalling cascade pathway
Cap-dependent Translation Initiation pathway
IRS-related events pathway
IGF1R signaling cascade pathway
Gene Expression pathway
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KEGG |
mTOR signaling pathway pathway
RNA transport pathway
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INOH | |||||||||||||||||||||||
PID NCI |
mTOR signaling pathway
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Hs.618114 Hs.648394 Hs.702041 Hs.729387 | ||||||||||||||||||||||
RefSeq | NM_001300821 NM_001417 XM_005268709 XM_006719274 | ||||||||||||||||||||||
HUGO | |||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS41788 CCDS73474 | ||||||||||||||||||||||
HPRD | 04892 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||