Version 5.4
Bos taurus Gene: UNC119
Summary
InnateDB Gene IDBG-631679.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UNC119
Gene Name Protein unc-119 homolog A
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013096
Encoded Proteins
IDBP-683233
Protein unc-119 homolog A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109103:
This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:20567270-20572913
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017411 ENSBTAP00000017411
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 80 interaction(s) predicted by orthology.
Predicted by orthology
Total 80 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
Biological Process
GO:0006810 transport
GO:0007109 cytokinesis, completion of separation
GO:0007601 visual perception
GO:0015031 protein transport
GO:0042953 lipoprotein transport
GO:0050896 response to stimulus
GO:0061098 positive regulation of protein tyrosine kinase activity
GO:1900186 negative regulation of clathrin-mediated endocytosis
GO:2001287 negative regulation of caveolin-mediated endocytosis
Cellular Component
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005856 cytoskeleton
GO:0045171 intercellular bridge
GO:0051233 spindle midzone
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000109103
View Gene Order
ENSMUSG00000002058
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
NetPath_17
IL5 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3SYR2
TrEMBL
UniProt Splice Variant
Entrez Gene 538501
UniGene Bt.48955
RefSeq NM_001034645
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103449
GenPept AAI03450
RNA Seq Atlas 538501

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca