Version 5.4
Bos taurus Gene: GAB3
Summary
InnateDB Gene IDBG-632149.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GAB3
Gene Name GRB2-associated-binding protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013044
Encoded Proteins
IDBP-683746
GRB2-associated binding protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160219:
This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:39064089-39147727
Strand Forward strand
Band
Transcripts
ENSBTAT00000017338 ENSBTAP00000017338
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030225 macrophage differentiation
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000160219
View Gene Order
ENSMUSG00000032750
View Gene Order
Cross-References
SwissProt
TrEMBL G3X716
UniProt Splice Variant
Entrez Gene 512009
UniGene Bt.44823
RefSeq NM_001192307 XM_005227646
HUGO HGNC:17515
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02070028
GenPept
RNA Seq Atlas 512009

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca