InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.18733

Summary

InnateDB Gene

IDBG-632187.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.18733

Gene Name

hexaprenyldihydroxybenzoate methyltransferase, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000019729

Encoded Proteins

IDBP-683787

hexaprenyldihydroxybenzoate methyltransferase, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132423:
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:51053688-51077746

Strand

Forward strand

Band

Transcripts

ENSBTAT00000026292

ENSBTAP00000026292

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008168	methyltransferase activity
GO:0008276	protein methyltransferase activity
GO:0008425	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity

Biological Process

GO:0006071	glycerol metabolic process
GO:0006479	protein methylation
GO:0006744	ubiquinone biosynthetic process
GO:0008152	metabolic process
GO:0008610	lipid biosynthetic process
GO:0009312	oligosaccharide biosynthetic process
GO:0009877	nodulation
GO:0032259	methylation