Bos taurus Gene: EFNA4
Summary
InnateDB Gene IDBG-632241.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EFNA4
Gene Name ephrin-A4 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010673
Encoded Proteins
ephrin-A4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000243364:
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:15587570-15591685
Strand Reverse strand
Band
Transcripts
ENSBTAT00000033972 ENSBTAP00000033875
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046875 ephrin receptor binding
Biological Process
GO:0007411 axon guidance
GO:0030316 osteoclast differentiation
GO:0046849 bone remodeling
GO:0048013 ephrin receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
EPHA-mediated growth cone collapse pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
Axon guidance pathway
Developmental Biology pathway
Developmental Biology pathway
Axon guidance pathway
EPHA-mediated growth cone collapse pathway
EPH-ephrin mediated repulsion of cells pathway
EPH-Ephrin signaling pathway
KEGG
Axon guidance pathway
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6QLY0
UniProt Splice Variant
Entrez Gene 615879
UniGene Bt.20476
RefSeq NM_001101249 XM_005203747
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC148126 DAAA02007156
GenPept AAI48127
RNA Seq Atlas 615879