Version 5.4
| Bos taurus Gene: CYP39A1 | |||||||||||||||
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| Summary | |||||||||||||||
| InnateDB Gene | IDBG-632292.3 | ||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
| Gene Symbol | CYP39A1 | ||||||||||||||
| Gene Name | 24-hydroxycholesterol 7-alpha-hydroxylase | ||||||||||||||
| Synonyms | |||||||||||||||
| Species | Bos taurus | ||||||||||||||
| Ensembl Gene | ENSBTAG00000003632 | ||||||||||||||
| Encoded Proteins |
24-hydroxycholesterol 7-alpha-hydroxylase
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| Protein Structure | |||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
| Entrez Gene | |||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146233:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||
| Type | Protein coding | ||||||||||||||
| Genomic Location | Chromosome 23:19776642-19860368 | ||||||||||||||
| Strand | Reverse strand | ||||||||||||||
| Band | |||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME |
Synthesis of bile acids and bile salts via 24-hydroxycholesterol pathway
Synthesis of bile acids and bile salts pathway
Endogenous sterols pathway
Metabolism of lipids and lipoproteins pathway
Bile acid and bile salt metabolism pathway
Cytochrome P450 - arranged by substrate type pathway
Metabolism pathway
Biological oxidations pathway
Phase 1 - Functionalization of compounds pathway
Cytochrome P450 - arranged by substrate type pathway
Phase 1 - Functionalization of compounds pathway
Synthesis of bile acids and bile salts via 24-hydroxycholesterol pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Endogenous sterols pathway
Synthesis of bile acids and bile salts pathway
Biological oxidations pathway
Bile acid and bile salt metabolism pathway
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| KEGG |
Primary bile acid biosynthesis pathway
Primary bile acid biosynthesis pathway
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| INOH | |||||||||||||||
| PID NCI | |||||||||||||||
| Cross-References | |||||||||||||||
| SwissProt | |||||||||||||||
| TrEMBL | A6H722 | ||||||||||||||
| UniProt Splice Variant | |||||||||||||||
| Entrez Gene | 511195 | ||||||||||||||
| UniGene | Bt.14369 | ||||||||||||||
| RefSeq | NM_001098938 | ||||||||||||||
| HUGO | |||||||||||||||
| OMIM | |||||||||||||||
| CCDS | |||||||||||||||
| HPRD | |||||||||||||||
| IMGT | |||||||||||||||
| EMBL | BC146085 DAAA02055161 DAAA02055162 | ||||||||||||||
| GenPept | AAI46086 | ||||||||||||||
| RNA Seq Atlas | 511195 | ||||||||||||||