InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: DHRS3

Summary

InnateDB Gene

IDBG-632328.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DHRS3

Gene Name

short-chain dehydrogenase/reductase 3

Synonyms

retSDR1; SDR1

Species

Bos taurus

Ensembl Gene

ENSBTAG00000024493

Encoded Proteins

IDBP-683933

short-chain dehydrogenase/reductase 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162496:
Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:41985339-42040600

Strand

Forward strand

Band

Transcripts

ENSBTAT00000034028

ENSBTAP00000033930

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004745	retinol dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0050662	coenzyme binding

Biological Process

GO:0001523	retinoid metabolic process
GO:0003151	outflow tract morphogenesis
GO:0008152	metabolic process
GO:0009058	biosynthetic process
GO:0030278	regulation of ossification
GO:0048387	negative regulation of retinoic acid receptor signaling pathway
GO:0055114	oxidation-reduction process
GO:0060021	palate development
GO:0060349	bone morphogenesis
GO:0060411	cardiac septum morphogenesis