Bos taurus Gene: SDHA | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-632600.2 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | SDHA | ||||||||||||
Gene Name | succinate dehydrogenase | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000046019 | ||||||||||||
Encoded Proteins |
succinate dehydrogenase
succinate dehydrogenase
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000073578:
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. [provided by RefSeq, Jul 2008] This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 20:71940743-71964107 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Respiratory electron transport pathway
Citric acid cycle (TCA cycle) pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Respiratory electron transport pathway
Metabolism pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Citric acid cycle (TCA cycle) pathway
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KEGG |
Citrate cycle (TCA cycle) pathway
Alzheimer's disease pathway
Oxidative phosphorylation pathway
Parkinson's disease pathway
Huntington's disease pathway
Oxidative phosphorylation pathway
Alzheimer's disease pathway
Citrate cycle (TCA cycle) pathway
Parkinson's disease pathway
Huntington's disease pathway
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INOH |
Arginine Proline metabolism pathway
Citrate cycle pathway
Tyrosine metabolism pathway
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PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | G5E6M7 H6S1N9 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 281480 | ||||||||||||
UniGene | Bt.24449 | ||||||||||||
RefSeq | NM_174178 XM_005221657 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | DAAA02051474 GU817012 | ||||||||||||
GenPept | ADX21068 | ||||||||||||
RNA Seq Atlas | 281480 | ||||||||||||
Transcript Frequencies | |||||||||||||
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).
Based on Data from Bovine Gene Atlas |
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