InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PNPLA8

Summary

InnateDB Gene

IDBG-632649.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PNPLA8

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000024387

Encoded Proteins

IDBP-684297

patatin-like phospholipase domain containing 8

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135241:
This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:49867702-49907595

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000017658

ENSBTAP00000017658

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0047499	calcium-independent phospholipase A2 activity

Biological Process

GO:0001516	prostaglandin biosynthetic process
GO:0006629	lipid metabolic process
GO:0006631	fatty acid metabolic process
GO:0008152	metabolic process
GO:0008219	cell death
GO:0019369	arachidonic acid metabolic process
GO:0034638	phosphatidylcholine catabolic process
GO:0043651	linoleic acid metabolic process
GO:0046338	phosphatidylethanolamine catabolic process
GO:0050482	arachidonic acid secretion