Version 5.4
Bos taurus Gene: CACNB3
Summary
InnateDB Gene IDBG-632790.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CACNB3
Gene Name Voltage-dependent L-type calcium channel subunit beta-3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021808
Encoded Proteins
IDBP-684443
Voltage-dependent L-type calcium channel subunit beta-3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167535:
This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:31116984-31126056
Strand Reverse strand
Band
Transcripts
ENSBTAT00000029069 ENSBTAP00000029069
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005244 voltage-gated ion channel activity
GO:0005245 voltage-gated calcium channel activity
GO:0005262 calcium channel activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0050852 T cell receptor signaling pathway
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005891 voltage-gated calcium channel complex
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000167535
View Gene Order
ENSMUSG00000003352
View Gene Order
Pathways
NETPATH
REACTOME
REACT_220819
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels pathway
REACT_209110
Regulation of insulin secretion pathway
REACT_217282
NCAM signaling for neurite out-growth pathway
REACT_202514
NCAM1 interactions pathway
REACT_217101
Integration of energy metabolism pathway
REACT_223058
Transmission across Chemical Synapses pathway
REACT_203140
Axon guidance pathway
REACT_225032
Neuronal System pathway
REACT_219139
Metabolism pathway
REACT_220844
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18339
Adrenaline,noradrenaline inhibits insulin secretion pathway
REACT_18325
Regulation of insulin secretion pathway
REACT_1505
Integration of energy metabolism pathway
REACT_18312
NCAM1 interactions pathway
REACT_18334
NCAM signaling for neurite out-growth pathway
REACT_111045
Developmental Biology pathway
REACT_13685
Neuronal System pathway
REACT_18266
Axon guidance pathway
REACT_13606
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_111217
Metabolism pathway
REACT_217323
Integration of energy metabolism pathway
REACT_236183
NCAM1 interactions pathway
REACT_188937
Metabolism pathway
REACT_263148
Regulation of insulin secretion pathway
REACT_261444
Axon guidance pathway
REACT_225645
Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels pathway
REACT_259290
Neuronal System pathway
REACT_188576
Developmental Biology pathway
REACT_233318
Transmission across Chemical Synapses pathway
REACT_237796
NCAM signaling for neurite out-growth pathway
KEGG
hsa04010
MAPK signaling pathway pathway
hsa05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
hsa05410
Hypertrophic cardiomyopathy (HCM) pathway
hsa04260
Cardiac muscle contraction pathway
hsa05414
Dilated cardiomyopathy pathway
mmu04010
MAPK signaling pathway pathway
mmu04260
Cardiac muscle contraction pathway
mmu05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
mmu05410
Hypertrophic cardiomyopathy (HCM) pathway
mmu05414
Dilated cardiomyopathy pathway
INOH
INOH website
GPCR Dopamine D1like receptor signaling pathway pathway
INOH website
GPCR Dopamine D1like receptor signaling pathway pathway
PID NCI
Cross-References
SwissProt Q9MZL3
TrEMBL
UniProt Splice Variant
Entrez Gene 282160
UniGene Bt.5478
RefSeq NM_174509 XM_005206257 XM_005206258 XM_005206260
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF174419 BC123784
GenPept AAF26683 AAI23785
RNA Seq Atlas 282160

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca