Version 5.4
Bos taurus Gene: BT.57034
Summary
InnateDB Gene IDBG-632793.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.57034
Gene Name 5'-nucleotidase precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000045976
Encoded Proteins
IDBP-684450
5'-nucleotidase precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135318:
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:64859552-64870020
Strand Forward strand
Band
Transcripts
ENSBTAT00000064900 ENSBTAP00000054917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0009166 nucleotide catabolic process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000135318
View Gene Order
ENSMUSG00000032420
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1023
Pyrimidine catabolism pathway
REACT_2086
Purine catabolism pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_957
Pyrimidine metabolism pathway
REACT_111217
Metabolism pathway
REACT_236186
Pyrimidine metabolism pathway
REACT_263730
Purine metabolism pathway
REACT_188937
Metabolism pathway
REACT_241108
Pyrimidine catabolism pathway
REACT_245662
Metabolism of nucleotides pathway
REACT_253802
Purine catabolism pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00760
Nicotinate and nicotinamide metabolism pathway
hsa00230
Purine metabolism pathway
mmu00760
Nicotinate and nicotinamide metabolism pathway
mmu00240
Pyrimidine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
INOH website
Nicotinate Nicotinamide metabolism pathway
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
hif1_tfpathway
HIF-1-alpha transcription factor network
Cross-References
SwissProt
TrEMBL G3MZC1
UniProt Splice Variant
Entrez Gene 281363
UniGene Bt.57034
RefSeq NM_174129
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02026517
GenPept
RNA Seq Atlas 281363
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca