InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: EMD

Summary

InnateDB Gene

IDBG-632864.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EMD

Gene Name

emerin

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000022314

Encoded Proteins

IDBP-684530

emerin

IDBP-684532

emerin

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102119:
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:40341311-40343613

Strand

Forward strand

Band

Transcripts

ENSBTAT00000030192	ENSBTAP00000030177
ENSBTAT00000054439	ENSBTAP00000051411

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 87 interaction(s) predicted by orthology.

Predicted by orthology
Total	87 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding
GO:0048487	beta-tubulin binding

Biological Process

GO:0035414	negative regulation of catenin import into nucleus
GO:0035914	skeletal muscle cell differentiation
GO:0046827	positive regulation of protein export from nucleus
GO:0048147	negative regulation of fibroblast proliferation
GO:0060828	regulation of canonical Wnt signaling pathway
GO:0071363	cellular response to growth factor stimulus

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005640	nuclear outer membrane
GO:0005783	endoplasmic reticulum
GO:0016020	membrane
GO:0031965	nuclear membrane