InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PTH

Summary

InnateDB Gene

IDBG-632953.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTH

Gene Name

Parathyroid hormone

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000019080

Encoded Proteins

IDBP-684617

Parathyroid hormone

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152266:
The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:39728332-39730868

Strand

Forward strand

Band

Transcripts

ENSBTAT00000025399

ENSBTAP00000025399

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005179	hormone activity
GO:0051428	peptide hormone receptor binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0006874	cellular calcium ion homeostasis
GO:0009967	positive regulation of signal transduction
GO:0010468	regulation of gene expression
GO:0030501	positive regulation of bone mineralization
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0034645	cellular macromolecule biosynthetic process
GO:0045725	positive regulation of glycogen biosynthetic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0046326	positive regulation of glucose import