Version 5.4
Bos taurus Gene: IQCB1
Summary
InnateDB Gene IDBG-633092.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IQCB1
Gene Name IQ calmodulin-binding motif-containing protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013069
Encoded Proteins
IDBP-684766
IQ calmodulin-binding motif-containing protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173226:
This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:66854942-66900462
Strand Reverse strand
Band
Transcripts
ENSBTAT00000017379 ENSBTAP00000017379
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 235 interaction(s) predicted by orthology.
Predicted by orthology
Total 235 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0019899 enzyme binding
Biological Process
GO:0042384 cilium assembly
GO:0045494 photoreceptor cell maintenance
GO:0048496 maintenance of organ identity
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0005634 nucleus
GO:0005813 centrosome
GO:0015630 microtubule cytoskeleton
GO:0032391 photoreceptor connecting cilium
GO:0045171 intercellular bridge
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000173226
View Gene Order
ENSMUSG00000022837
View Gene Order
Cross-References
SwissProt
TrEMBL Q29RS3
UniProt Splice Variant
Entrez Gene 534598
UniGene Bt.64379
RefSeq NM_001046381 XM_005201401 XM_005201402
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114049 DAAA02001588 DAAA02001589
GenPept AAI14050
RNA Seq Atlas 534598

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca