Version 5.4
Bos taurus Gene: HVCN1
Summary
InnateDB Gene IDBG-633167.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HVCN1
Gene Name voltage-gated hydrogen channel 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009216
Encoded Proteins
IDBP-684853
hydrogen voltage-gated channel 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122986:
This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:56752248-56763493
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012146 ENSBTAP00000012146
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005244 voltage-gated ion channel activity
GO:0030171 voltage-gated proton channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0009268 response to pH
GO:0010043 response to zinc ion
GO:0015992 proton transport
GO:0034220 ion transmembrane transport
GO:0034765 regulation of ion transmembrane transport
GO:0055085 transmembrane transport
GO:0071294 cellular response to zinc ion
GO:0071467 cellular response to pH
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000122986
View Gene Order
ENSMUSG00000064267
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_163914
Fertilization pathway
REACT_163875
Sperm Motility And Taxes pathway
REACT_163848
Reproduction pathway
REACT_196630
Sperm Motility And Taxes pathway
REACT_199082
Fertilization pathway
REACT_199085
Reproduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.105405 Bt.111707
RefSeq NM_001206253 XM_005217923 XM_005217924 XM_005217925
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca