Version 5.4
Bos taurus Gene: BMPER
Summary
InnateDB Gene IDBG-633233.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BMPER
Gene Name BMP-binding endothelial regulator protein precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010866
Encoded Proteins
IDBP-684924
BMP-binding endothelial regulator protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164619:
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:63052088-63305357
Strand Reverse strand
Band
Transcripts
ENSBTAT00000046295 ENSBTAP00000043607
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001657 ureteric bud development
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:0010594 regulation of endothelial cell migration
GO:0030514 negative regulation of BMP signaling pathway
GO:0042118 endothelial cell activation
GO:0048839 inner ear development
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164619
View Gene Order
ENSMUSG00000031963
View Gene Order
Cross-References
SwissProt
TrEMBL A0JNC8
UniProt Splice Variant
Entrez Gene 534101
UniGene Bt.2739
RefSeq NM_001077997
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126620 DAAA02010845 DAAA02010846 DAAA02010847 DAAA02010848 DAAA02010849 DAAA02010850 DAAA02010851
GenPept AAI26621
RNA Seq Atlas 534101

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca