InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ENPP3

Summary

InnateDB Gene

IDBG-633291.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ENPP3

Gene Name

ectonucleotide pyrophosphatase/phosphodiesterase family member 3

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000020196

Encoded Proteins

IDBP-684994

ectonucleotide pyrophosphatase/phosphodiesterase family member 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154269:
The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:70588607-70673279

Strand

Forward strand

Band

Transcripts

ENSBTAT00000026900

ENSBTAP00000026900

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003824	catalytic activity
GO:0005044	scavenger receptor activity
GO:0016787	hydrolase activity
GO:0030247	polysaccharide binding
GO:0046872	metal ion binding
GO:0047429	nucleoside-triphosphate diphosphatase activity

Biological Process

GO:0006796	phosphate-containing compound metabolic process
GO:0006898	receptor-mediated endocytosis
GO:0006955	immune response
GO:0008152	metabolic process
GO:0009143	nucleoside triphosphate catabolic process