Bos taurus Gene: BT.40523
Summary
InnateDB Gene IDBG-633299.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.40523
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015264
Encoded Proteins
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083457:
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:25004111-25047400
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020307 ENSBTAP00000020307
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway
Cellular Component
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Integrin cell surface interactions pathway
Extracellular matrix organization pathway
Extracellular matrix organization pathway
Integrin cell surface interactions pathway
KEGG
Regulation of actin cytoskeleton pathway
Regulation of actin cytoskeleton pathway
INOH
Integrin signaling pathway pathway
Integrin signaling pathway pathway
PID NCI
E-cadherin signaling in the nascent adherens junction
Integrin family cell surface interactions
AlphaE beta7 integrin cell surface interactions
Cross-References
SwissProt
TrEMBL E1BFX5
UniProt Splice Variant
Entrez Gene 100140050
UniGene Bt.40523
RefSeq XM_001788129 XM_002695790
HUGO HGNC:6147
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048691
GenPept
RNA Seq Atlas 100140050