Bos taurus Gene: BT.40523 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-633299.3 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | BT.40523 | ||||||||
Gene Name | Uncharacterized protein | ||||||||
Synonyms | |||||||||
Species | Bos taurus | ||||||||
Ensembl Gene | ENSBTAG00000015264 | ||||||||
Encoded Proteins |
Uncharacterized protein
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083457:
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 19:25004111-25047400 | ||||||||
Strand | Reverse strand | ||||||||
Band | |||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Integrin cell surface interactions pathway
Extracellular matrix organization pathway
Extracellular matrix organization pathway
Integrin cell surface interactions pathway
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KEGG |
Regulation of actin cytoskeleton pathway
Regulation of actin cytoskeleton pathway
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INOH |
Integrin signaling pathway pathway
Integrin signaling pathway pathway
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PID NCI |
E-cadherin signaling in the nascent adherens junction
Integrin family cell surface interactions
AlphaE beta7 integrin cell surface interactions
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | E1BFX5 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 100140050 | ||||||||
UniGene | Bt.40523 | ||||||||
RefSeq | XM_001788129 XM_002695790 | ||||||||
HUGO | HGNC:6147 | ||||||||
OMIM | |||||||||
CCDS | |||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | DAAA02048691 | ||||||||
GenPept | |||||||||
RNA Seq Atlas | 100140050 | ||||||||