Version 5.4
Bos taurus Gene: SF3B4
Summary
InnateDB Gene IDBG-633476.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SF3B4
Gene Name splicing factor 3B subunit 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012495
Encoded Proteins
IDBP-685220
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143368:
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:20727610-20731285
Strand Forward strand
Band
Transcripts
ENSBTAT00000016577 ENSBTAP00000016577
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 74 interaction(s) predicted by orthology.
Predicted by orthology
Total 74 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
Biological Process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143368
View Gene Order
ENSMUSG00000068856
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_1753
mRNA Splicing - Minor Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
REACT_249110
mRNA Splicing pathway
REACT_235610
mRNA Splicing - Minor Pathway pathway
REACT_233572
Gene Expression pathway
REACT_260226
mRNA Splicing - Major Pathway pathway
REACT_233950
Processing of Capped Intron-Containing Pre-mRNA pathway
KEGG
hsa03040
Spliceosome pathway
mmu03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MWR2 Q3MHE6
UniProt Splice Variant
Entrez Gene 506123
UniGene Bt.3914
RefSeq NM_001205584
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105266 DAAA02007272
GenPept AAI05267
RNA Seq Atlas 506123

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca