Version 5.4
Bos taurus Gene: BT.87350
Summary
InnateDB Gene IDBG-633600.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.87350
Gene Name homeobox protein Hox-A2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008138
Encoded Proteins
IDBP-685311
homeobox protein Hox-A2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105996:
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:69394241-69396203
Strand Forward strand
Band
Transcripts
ENSBTAT00000010699 ENSBTAP00000010699
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001709 cell fate determination
GO:0002076 osteoblast development
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0007379 segment specification
GO:0007389 pattern specification process
GO:0008045 motor neuron axon guidance
GO:0009952 anterior/posterior pattern specification
GO:0009953 dorsal/ventral pattern formation
GO:0021568 rhombomere 2 development
GO:0021569 rhombomere 3 development
GO:0021658 rhombomere 3 morphogenesis
GO:0035284 brain segmentation
GO:0042474 middle ear morphogenesis
GO:0045165 cell fate commitment
GO:0045665 negative regulation of neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048703 embryonic viscerocranium morphogenesis
GO:0048704 embryonic skeletal system morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000105996
View Gene Order
ENSMUSG00000014704
View Gene Order
Cross-References
SwissProt
TrEMBL F1MD21
UniProt Splice Variant
Entrez Gene 524150
UniGene Bt.111374
RefSeq NM_001075854
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010939
GenPept
RNA Seq Atlas 524150

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca